{"id":3437,"date":"2023-09-11T15:00:58","date_gmt":"2023-09-11T12:00:58","guid":{"rendered":"https:\/\/ablebook.com.cy\/?p=3437"},"modified":"2023-09-11T15:00:59","modified_gmt":"2023-09-11T12:00:59","slug":"e%ce%bb%cf%80%ce%af%ce%b4%ce%b5%cf%82-%ce%b3%ce%b9%ce%b1-%ce%b1%ce%bd%ce%b1%cf%87%ce%b1%ce%af%cf%84%ce%b9%cf%83%ce%b7-%cf%84%ce%b7%cf%82-%ce%bc%cf%85%ce%bf%cf%80%ce%ac%ce%b8%ce%b5%ce%b9%ce%b1%cf%82-du","status":"publish","type":"post","link":"https:\/\/ablebook.com.cy\/el\/e%ce%bb%cf%80%ce%af%ce%b4%ce%b5%cf%82-%ce%b3%ce%b9%ce%b1-%ce%b1%ce%bd%ce%b1%cf%87%ce%b1%ce%af%cf%84%ce%b9%cf%83%ce%b7-%cf%84%ce%b7%cf%82-%ce%bc%cf%85%ce%bf%cf%80%ce%ac%ce%b8%ce%b5%ce%b9%ce%b1%cf%82-du\/","title":{"rendered":"E\u03bb\u03c0\u03af\u03b4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03b1\u03c7\u03b1\u03af\u03c4\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1\u03c2 Duchenne"},"content":{"rendered":"\n

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\u0397 \u03b4\u03b9\u03b1\u03c7\u03b5\u03af\u03c1\u03b9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u039c\u03c5\u03ca\u03ba\u03ae\u03c2 \u0394\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03b1\u03c2 Duchenne \u03b1\u03c0\u03b1\u03b9\u03c4\u03b5\u03af \u03c4\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03c0\u03bf\u03bb\u03c5\u03b8\u03b5\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03b1\u03c0\u03cc \u03ad\u03bc\u03c0\u03b5\u03b9\u03c1\u03bf\u03c5\u03c2 \u03b9\u03b1\u03c4\u03c1\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ca\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc \u03bc\u03b5  \u03c0\u03bf\u03bb\u03bb\u03b1\u03c0\u03bb\u03ad\u03c2 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03b9\u03ba\u03c4\u03b9\u03ba\u03ad\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2.  \u038c\u03c4\u03b1\u03bd \u03ad\u03bd\u03b1 \u03b1\u03b3\u03cc\u03c1\u03b9 \u03b4\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b5\u03af \u03bc\u03b5 DMD, \u03b5\u03af\u03bd\u03b1\u03b9 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03cc \u03bd\u03b1 \u03b1\u03bd\u03b1\u03b6\u03b7\u03c4\u03b7\u03b8\u03b5\u03af \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03ae \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b3\u03af\u03bd\u03bf\u03c5\u03bd \u03bf\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03bf\u03b9 \u03ad\u03bb\u03b5\u03b3\u03c7\u03bf\u03b9 \u03c3\u03c4\u03b1 \u03bc\u03ad\u03bb\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03b9\u03ba\u03bf\u03b3\u03ad\u03bd\u03b5\u03b9\u03b1\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03b9\u03b8\u03b1\u03bd\u03cc \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c6\u03bf\u03c1\u03b5\u03af\u03c2 \u03ae \u03c0\u03bf\u03c5 \u03ba\u03b9\u03bd\u03b4\u03c5\u03bd\u03b5\u03cd\u03bf\u03c5\u03bd \u03bd\u03b1 \u03bd\u03bf\u03c3\u03ae\u03c3\u03bf\u03c5\u03bd. \u03a6\u03c5\u03c3\u03b9\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1, \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b4\u03c5\u03b1\u03c3\u03bc\u03cc \u03bc\u03b5 \u03bf\u03c1\u03b8\u03bf\u03c4\u03b9\u03ba\u03ac \u03b2\u03bf\u03b7\u03b8\u03ae\u03bc\u03b1\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03c1\u03bf\u03c7\u03bf\u03ba\u03b1\u03b8\u03af\u03c3\u03bc\u03b1\u03c4\u03b1, \u03bf\u03c1\u03b8\u03bf\u03c0\u03b5\u03b4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03c0\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03cc\u03c4\u03b1\u03bd \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9, \u03ba\u03b1\u03b9 \u03c3\u03c5\u03bc\u03c0\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c6\u03b1\u03c1\u03bc\u03b1\u03ba\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b1\u03b3\u03c9\u03b3\u03ae \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b9\u03c2 \u03c0\u03b5\u03c1\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03ac\u03b8\u03b7\u03c3\u03b7\u03c2, \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03b9\u03ba\u03cc\u03c4\u03b7\u03c4\u03b1 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03bf\u03b9\u03cc\u03c4\u03b7\u03c4\u03b1 \u03b6\u03c9\u03ae\u03c2.<\/p>\n\n\n\n

\u039a\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2<\/strong><\/p>\n\n\n\n

\u039a\u03b1\u03b9\u03bd\u03bf\u03c4\u03cc\u03bc\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u039c\u03c5\u03ca\u03ba\u03ae\u03c2 \u0394\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03b1\u03c2 Duchenne \u03ad\u03c7\u03bf\u03c5\u03bd \u03b5\u03b9\u03c3\u03b1\u03c7\u03b8\u03b5\u03af \u03c4\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c3\u03c4\u03b7\u03bd \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03c0\u03c1\u03b1\u03ba\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03ae \u03c3\u03c4\u03b1 \u03c0\u03c1\u03cc\u03b8\u03c5\u03c1\u03b1 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ce\u03bd \u03b4\u03bf\u03ba\u03b9\u03bc\u03ce\u03bd. \u039f\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03b1\u03c0\u03bf\u03c3\u03ba\u03bf\u03c0\u03bf\u03cd\u03bd \u03c3\u03c4\u03b7\u03bd \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03bf\u03c3\u03cc\u03c4\u03b7\u03c4\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03bc\u03cd\u03b5\u03c2. \u039b\u03cc\u03b3\u03c9 \u03c4\u03bf\u03c5 \u03bc\u03b5\u03b3\u03ac\u03bb\u03bf\u03c5 \u03bc\u03b5\u03b3\u03ad\u03b8\u03bf\u03c5\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 \u03c4\u03b7\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2, \u03b5\u03af\u03bd\u03b1\u03b9 \u03b4\u03cd\u03c3\u03ba\u03bf\u03bb\u03bf \u03bd\u03b1 \u03bc\u03b5\u03c4\u03b1\u03c6\u03b5\u03c1\u03b8\u03b5\u03af \u03bc\u03ad\u03c3\u03c9 \u03b9\u03ca\u03ba\u03ce\u03bd \u03c6\u03bf\u03c1\u03ad\u03c9\u03bd \u03c3\u03c4\u03bf \u03c3\u03ce\u03bc\u03b1. \u0395\u03c0\u03bf\u03bc\u03ad\u03bd\u03c9\u03c2  \u03b7 \u03b5\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03bf\u03bd\u03b5\u03c2 \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03bc\u03b9\u03b1\u03c2 \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03bf\u03c5 \u03bc\u03b5\u03b3\u03ad\u03b8\u03bf\u03c5\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2, \u03b5\u03af\u03c4\u03b5 \u03bc\u03ad\u03c3\u03c9 \u03b1\u03bd\u03c4\u03b9\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7\u03c2 \u03b5\u03bd\u03cc\u03c2 \u03bc\u03af\u03bd\u03b9-\u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5 DMD (gene replacement), \u03b5\u03af\u03c4\u03b5 \u03bc\u03ad\u03c3\u03c9 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03bf\u03bb\u03ae\u03c2 \u03c3\u03c4\u03bf \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03bf mRNA \u03b3\u03b9\u03b1 \u03b1\u03c0\u03bf\u03c4\u03c1\u03bf\u03c0\u03ae \u03c4\u03b7\u03c2 \u03c0\u03c1\u03cc\u03c9\u03c1\u03b7\u03c2 \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03c1\u03bf\u03c6\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03c9\u03c4\u03b5\u0390\u03bd\u03b7\u03c2 \u03bb\u03cc\u03b3\u03c9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03c9\u03bd \u03bc\u03b5\u03c4\u03b1\u03bb\u03bb\u03ac\u03be\u03b5\u03c9\u03bd \u03c0\u03c1\u03cc\u03c9\u03c1\u03bf\u03c5 \u03c4\u03b5\u03c1\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03bf\u03cd (read-through for premature stop codons), \u03ae \u03bc\u03b5 \u03c5\u03c0\u03b5\u03c1\u03c0\u03ae\u03b4\u03b7\u03c3\u03b7 \u03b1\u03c3\u03cd\u03bc\u03b2\u03b1\u03c4\u03c9\u03bd \u03b5\u03be\u03bf\u03bd\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ba\u03cd\u03c0\u03c4\u03bf\u03c5\u03bd \u03b1\u03c0\u03cc \u03b4\u03b9\u03b1\u03b3\u03c1\u03b1\u03c6\u03ad\u03c2 \u03ae \u03b4\u03b9\u03c0\u03bb\u03b1\u03c3\u03b9\u03b1\u03c3\u03bc\u03bf\u03cd\u03c2 \u03c4\u03bf\u03c5 DNA (exon skipping) \u03ce\u03c3\u03c4\u03b5 \u03bd\u03b1 \u03b5\u03c0\u03b9\u03c4\u03b5\u03c5\u03c7\u03b8\u03b5\u03af \u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03bc\u03b9\u03ba\u03c1\u03cc\u03c4\u03b5\u03c1\u03b7\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2.<\/p>\n\n\n\n

\u03a3\u03b5 \u03bc\u03b9\u03b1 \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7, \u03c4\u03bf\u03bd \u03c0\u03b5\u03c1\u03b1\u03c3\u03bc\u03ad\u03bd\u03bf \u0399\u03bf\u03cd\u03bd\u03b9\u03bf, \u03b7 \u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03ae \u0391\u03c1\u03c7\u03ae \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03c4\u03c9\u03bd \u0397\u03a0\u0391 (FDA), \u03b5\u03bd\u03ad\u03ba\u03c1\u03b9\u03bd\u03b5 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c4\u03b1\u03c1\u03ba\u03c4\u03b9\u03ba\u03ac \u03b3\u03b9\u03b1 \u03c0\u03c1\u03ce\u03c4\u03b7 \u03c6\u03bf\u03c1\u03ac \u03c3\u03b5 \u03b5\u03c0\u03b5\u03af\u03b3\u03bf\u03c5\u03c3\u03b1 \u03c6\u03ac\u03c3\u03b7, \u03bc\u03b9\u03b1 \u03bd\u03ad\u03b1 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 DMD \u03b7\u03bb\u03b9\u03ba\u03af\u03b1\u03c2 4-5 \u03b5\u03c4\u03ce\u03bd (Elevidys). \u03a0\u03c1\u03cc\u03ba\u03b5\u03b9\u03c4\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03bc\u03b9\u03b1 \u03ad\u03bd\u03b1 \u03b1\u03b4\u03b5\u03bd\u03bf-\u03c3\u03c7\u03b5\u03c4\u03b9\u03b6\u03cc\u03bc\u03b5\u03bd\u03bf \u03b9\u03ca\u03ba\u03cc \u03c6\u03bf\u03c1\u03ad\u03b1 (Adeno-associated viral, AAV vector) o \u03bf\u03c0\u03bf\u03af\u03bf\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03b5\u03bd\u03b4\u03bf\u03c6\u03bb\u03ad\u03b2\u03b9\u03b1 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c3\u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c4\u03bf\u03c5 \u03c3\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf \u03c4\u03b5\u03c7\u03bd\u03b7\u03c4\u03cc \u03b3\u03bf\u03bd\u03af\u03b4\u03b9\u03bf \u03bc\u03b9\u03b1\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf-\u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03c1\u03c7\u03af\u03b6\u03b5\u03b9 \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ac\u03b3\u03b5\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b1\u03bd\u03b1\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03b5\u03b9 \u03bc\u03ad\u03c1\u03bf\u03c2 \u03c4\u03b7\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03c4\u03b7\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2 \u03bc\u03ad\u03c3\u03b1 \u03c3\u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1.  \u0397 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 EMBAR\u039a, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03c3\u03c5\u03bd\u03b5\u03c7\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b1 \u03c3\u03b5 140 \u03c0\u03b1\u03b9\u03b4\u03b9\u03ac \u03bc\u03b5 DMD \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03c0\u03c1\u03bf\u03ba\u03b1\u03c4\u03b1\u03c1\u03ba\u03c4\u03b9\u03ba\u03ac \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03c4\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf-\u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b5\u03b9\u03ba\u03cc\u03bd\u03b1\u03c2 \u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03ae \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03b9\u03b1\u03ba\u03ae \u03bf\u03bc\u03ac\u03b4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd. \u03a4\u03b1 \u03b1\u03bd\u03b1\u03bc\u03b5\u03bd\u03cc\u03bc\u03b5\u03bd\u03b1 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ac \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03ad\u03c3\u03bc\u03b1\u03c4\u03b1 \u03c4\u03b7\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ae\u03c2 \u03c6\u03ac\u03c3\u03b7\u03c2 3 \u03b8\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03bf\u03c5\u03bd \u03c3\u03c4\u03b7 \u03c4\u03b5\u03bb\u03b9\u03ba\u03ae \u03b5\u03c0\u03b9\u03b2\u03b5\u03b2\u03b1\u03af\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03af\u03c3\u03c9\u03c2 \u03ad\u03b3\u03ba\u03c1\u03b9\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03bf\u03c5.<\/p>\n\n\n\n

\u0395\u03c0\u03b9\u03c0\u03c1\u03cc\u03c3\u03b8\u03b5\u03c4\u03b1 \u03b1\u03c0\u03cc \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b1\u03c5\u03c4\u03ae, \u03c3\u03c4\u03bf \u03c0\u03b1\u03c1\u03cc\u03bd \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03b4\u03bf\u03ba\u03b9\u03bc\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b5\u03c2 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd DMD. \u0391\u03c5\u03c4\u03ad\u03c2 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03ac\u03bb\u03bb\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b1\u03bb\u03bb\u03b1\u03b3\u03ad\u03c2 \u03c4\u03b7\u03c2 \u03bc\u03b9\u03bd\u03b9-\u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03bd\u03b7\u03c2 \u03ae \u03c4\u03b7 \u03bc\u03b5\u03c4\u03b1\u03c6\u03bf\u03c1\u03ac \u03ac\u03bb\u03bb\u03c9\u03bd \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b1 \u03bc\u03c5\u03ca\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1.  \u039d\u03ad\u03b5\u03c2 \u03c4\u03b5\u03c7\u03bd\u03bf\u03bb\u03bf\u03b3\u03af\u03b5\u03c2 \u03bc\u03b1\u03c4\u03af\u03c3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03c4\u03bf\u03c5 \u03b3\u03bf\u03bd\u03b9\u03b4\u03af\u03bf\u03c5, \u03b4\u03b7\u03bb\u03b1\u03b4\u03ae \u03b5\u03c0\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 \u03bc\u03b5\u03b3\u03ac\u03bb\u03b7\u03c2 \u03b1\u03ba\u03c1\u03af\u03b2\u03b5\u03b9\u03b1\u03c2 \u03b3\u03b9\u03b1 \u03b5\u03c0\u03b9\u03b4\u03b9\u03cc\u03c1\u03b8\u03c9\u03c3\u03b7 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ce\u03bd \u03b2\u03bb\u03b1\u03b2\u03ce\u03bd (gene editing CRISPR\/Cas9, Prime editing) \u03b2\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03c3\u03b5 \u03c3\u03c4\u03ac\u03b4\u03b9\u03bf \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7\u03c2 \u03c3\u03b5 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03b1 \u03c4\u03b7\u03c2 DMD.  \u038c\u03bb\u03b5\u03c2 \u03b1\u03c5\u03c4\u03ad\u03c2 \u03bf\u03b9 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2 \u03b4\u03b7\u03bc\u03b9\u03bf\u03c5\u03c1\u03b3\u03bf\u03cd\u03bd \u03b5\u03bb\u03c0\u03af\u03b4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03bc\u03b9\u03b1 \u03ba\u03b1\u03bb\u03cd\u03c4\u03b5\u03c1\u03b7 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c0\u03b9\u03bf \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03ac\u03b8\u03b7\u03c3\u03b7\u03c2 \u03c3\u03c4\u03bf \u03b5\u03b3\u03b3\u03cd\u03c2 \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd.<\/p>\n\n\n\n

\u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u039d\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ce\u03bd \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd \u03c3\u03c4\u03b7\u03bd \u039a\u03cd\u03c0\u03c1\u03bf<\/strong><\/p>\n\n\n\n

\u03a3\u03c4\u03b7 \u03c7\u03ce\u03c1\u03b1 \u03bc\u03b1\u03c2, \u03c4\u03bf \u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u039d\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ce\u03bd \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd-\u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03bc\u03c5\u03ca\u03ba\u03ae\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03b1\u03c2 \u03c4\u03bf\u03c5 \u0399\u03bd\u03c3\u03c4\u03b9\u03c4\u03bf\u03cd\u03c4\u03bf\u03c5 \u039d\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 & \u0393\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u039a\u03cd\u03c0\u03c1\u03bf\u03c5, (\u0399\u039d\u0393\u039a) \u03c0\u03c1\u03c9\u03c4\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03af \u03c3\u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7, \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03bf\u03bb\u03c5\u03b8\u03b5\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03c4\u03c9\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03ce\u03bd \u03bc\u03b5 DMD \u03c4\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 30 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1.  \u03a4\u03bf \u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u03b1\u03c3\u03c7\u03bf\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd \u03cc\u03c0\u03c9\u03c2 \u03bf\u03b9 \u03bc\u03c5\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03c5\u03ca\u03ba\u03ad\u03c2 \u03b4\u03c5\u03c3\u03c4\u03c1\u03bf\u03c6\u03af\u03b5\u03c2, \u03b7 \u03bd\u03cc\u03c3\u03bf\u03c2 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03bf\u03cd \u03bd\u03b5\u03c5\u03c1\u03ce\u03bd\u03b1, \u03b7 \u03bc\u03c5\u03b1\u03c3\u03b8\u03ad\u03bd\u03b5\u03b9\u03b1, \u03ba\u03b1\u03b9 \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c6\u03b5\u03c1\u03b9\u03ba\u03ad\u03c2 \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b5\u03c2, \u03b5\u03bd\u03ce \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03bc\u03bf\u03bd\u03b1\u03b4\u03b9\u03ba\u03ac \u03c3\u03c4\u03b7\u03bd \u039a\u03cd\u03c0\u03c1\u03bf \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c1\u03b3\u03b1\u03c3\u03c4\u03ae\u03c1\u03b9\u03b1 \u03b7\u03bb\u03b5\u03ba\u03c4\u03c1\u03bf\u03bc\u03c5\u03bf\u03b3\u03c1\u03b1\u03c6\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2, \u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2, \u03bd\u03b5\u03c5\u03c1\u03bf\u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2, \u03b2\u03b9\u03bf\u03c7\u03b7\u03bc\u03b5\u03af\u03b1\u03c2, \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1. \u0395\u03c6\u03b1\u03c1\u03bc\u03cc\u03b6\u03b5\u03b9 \u03bd\u03ad\u03b5\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03be\u03b5\u03b9\u03b4\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03c3\u03b5 \u03b5\u03be\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03ba\u03b1\u03b9 \u03b5\u03c3\u03c9\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03b2\u03ac\u03c3\u03b7 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03c0\u03c1\u03c9\u03c4\u03cc\u03ba\u03bf\u03bb\u03bb\u03b1 \u03ba\u03b1\u03b9 \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03b9 \u03c0\u03bf\u03bb\u03c5\u03b8\u03b5\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1. \u0395\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03bf \u03ba\u03ad\u03bd\u03c4\u03c1\u03bf \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03b9\u03ba\u03ce\u03bd \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd \u03c4\u03c1\u03bf\u03c6\u03bf\u03b4\u03bf\u03c4\u03b5\u03af \u03c0\u03c1\u03c9\u03c4\u03bf\u03c0\u03bf\u03c1\u03b9\u03b1\u03ba\u03ac \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03b3\u03c1\u03ac\u03bc\u03bc\u03b1\u03c4\u03b1 \u03c0\u03bf\u03c5 \u03b1\u03c6\u03bf\u03c1\u03bf\u03cd\u03bd \u03c3\u03b5 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1, \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u03b5\u03ba\u03c0\u03b1\u03af\u03b4\u03b5\u03c5\u03c3\u03b7 \u03c3\u03b5 \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03ba\u03b1\u03b9 \u03c0\u03b1\u03c1\u03b1\u03ca\u03b1\u03c4\u03c1\u03b9\u03ba\u03cc \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc.  \u03a4\u03bf  \u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u039d\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ce\u03bd \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd \u03ad\u03b3\u03b9\u03bd\u03b5 \u03b1\u03c0\u03bf\u03b4\u03b5\u03ba\u03c4\u03cc \u03c3\u03b1\u03bd \u03c3\u03c5\u03bd\u03b4\u03b5\u03cc\u03bc\u03b5\u03bd\u03bf \u03bc\u03ad\u03bb\u03bf\u03c2 \u03c4\u03bf\u03c5 \u0395\u03c5\u03c1\u03c9\u03c0\u03b1\u03ca\u03ba\u03bf\u03cd \u0394\u03b9\u03ba\u03c4\u03cd\u03bf\u03c5 \u0391\u03bd\u03b1\u03c6\u03bf\u03c1\u03ac\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ad\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2 (ERN-Neuromuscular) \u03c0\u03bf\u03c5 \u03b5\u03b4\u03c1\u03b5\u03cd\u03b5\u03b9 \u03c3\u03c4\u03bf \u03a0\u03b1\u03c1\u03af\u03c3\u03b9 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03bf \u03bf\u03c0\u03bf\u03af\u03bf \u03c3\u03c5\u03bc\u03bc\u03b5\u03c4\u03ad\u03c7\u03bf\u03c5\u03bd  \u03ba\u03bf\u03c1\u03c5\u03c6\u03b1\u03af\u03b1 \u03b1\u03ba\u03b1\u03b4\u03b7\u03bc\u03b1\u03ca\u03ba\u03ac \u03b9\u03b4\u03c1\u03cd\u03bc\u03b1\u03c4\u03b1 \u03b1\u03c0\u03cc \u03cc\u03bb\u03b7 \u03c4\u03b7\u03bd \u0395\u03c5\u03c1\u03ce\u03c0\u03b7.<\/p>\n\n\n\n

\u03a3\u03c4\u03bf \u0399\u039d\u0393\u039a \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03b5\u03c4\u03b1\u03b9 \u03c0\u03bf\u03bb\u03c5\u03b8\u03b5\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c6\u03c1\u03bf\u03bd\u03c4\u03af\u03b4\u03b1 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ad\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2, \u03c0\u03bf\u03c5 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c0\u03bd\u03b5\u03c5\u03bc\u03bf\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf, \u03bf\u03c1\u03b8\u03bf\u03c0\u03b5\u03b4\u03b9\u03ba\u03cc, \u03ba\u03b1\u03c1\u03b4\u03b9\u03bf\u03bb\u03cc\u03b3\u03bf, \u03b5\u03bd\u03b4\u03bf\u03ba\u03c1\u03b9\u03bd\u03bf\u03bb\u03cc\u03b3\u03bf, \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf, \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03bf\u03bb\u03cc\u03b3\u03bf \u03ba\u03b1\u03b9 \u03bb\u03bf\u03b3\u03bf\u03c0\u03b1\u03b8\u03bf\u03bb\u03cc\u03b3\u03bf. \u0395\u03c0\u03af\u03c3\u03b7\u03c2 \u03c4\u03bf \u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c5\u03c0\u03b7\u03c1\u03b5\u03c3\u03af\u03b5\u03c2 \u03b3\u03b5\u03bd\u03b5\u03c4\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c5\u03bc\u03b2\u03bf\u03c5\u03bb\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae\u03c2, \u03c8\u03c5\u03c7\u03bf\u03bb\u03bf\u03b3\u03b9\u03ba\u03ae\u03c2 \u03c3\u03c4\u03ae\u03c1\u03b9\u03be\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03ba\u03bf\u03b9\u03bd\u03c9\u03bd\u03b9\u03ba\u03ae\u03c2 \u03c5\u03c0\u03b7\u03c1\u03b5\u03c3\u03af\u03b1\u03c2. \u0399\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b7 \u03ad\u03bc\u03c6\u03b1\u03c3\u03b7 \u03b4\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c6\u03c5\u03c3\u03b9\u03bf\u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bc\u03b5 \u03ac\u03c1\u03c4\u03b9\u03b1 \u03ba\u03b1\u03c4\u03b1\u03c1\u03c4\u03b9\u03c3\u03bc\u03ad\u03bd\u03bf \u03c0\u03c1\u03bf\u03c3\u03c9\u03c0\u03b9\u03ba\u03cc \u03b3\u03b9\u03b1 \u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03bf\u03bc\u03b1\u03b4\u03b9\u03ba\u03ae \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03c4\u03b9\u03bc\u03b5\u03c4\u03ce\u03c0\u03b9\u03c3\u03b7 \u03ba\u03b9\u03bd\u03b7\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03c1\u03bf\u03b2\u03bb\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd.<\/p>\n\n\n\n

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\u0394\u03b9\u03b1\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03c4\u03ac\u03c3\u03b5\u03b9\u03c2<\/strong><\/p>\n\n\n\n

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\u03a3\u03c4\u03bf \u039a\u03ad\u03bd\u03c4\u03c1\u03bf \u03b4\u03b9\u03b5\u03be\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u039d\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ce\u03bd \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03c6\u03c1\u03b1\u03c3\u03c4\u03b9\u03ba\u03ae \u03ba\u03b1\u03b9 \u03b2\u03b1\u03c3\u03b9\u03ba\u03ae \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1 \u03bc\u03b5 \u03b5\u03c0\u03af\u03ba\u03b5\u03bd\u03c4\u03c1\u03bf \u03c4\u03b7 \u03b4\u03b9\u03ac\u03b3\u03bd\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b1 \u03bd\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ce\u03bd \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03b9\u03ce\u03bd. \u0392\u03c1\u03af\u03c3\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03ae\u03bc\u03b5\u03c1\u03b1 \u03c3\u03b5 \u03b5\u03be\u03ad\u03bb\u03b9\u03be\u03b7 \u03c4\u03ad\u03c3\u03c3\u03b5\u03c1\u03b5\u03b9\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03bd\u03ad\u03c9\u03bd \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c6\u03b1\u03c1\u03bc\u03ac\u03ba\u03c9\u03bd \u03b3\u03b9\u03b1 \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03ae \u03b1\u03bc\u03c5\u03bb\u03bf\u03b5\u03b9\u03b4\u03b9\u03ba\u03ae \u03c0\u03bf\u03bb\u03c5\u03bd\u03b5\u03c5\u03c1\u03bf\u03c0\u03ac\u03b8\u03b5\u03b9\u03b1 (FAP) \u03ba\u03b1\u03b9 \u03b3\u03b9\u03b1 \u03b1\u03c5\u03c4\u03bf\u03ac\u03bd\u03bf\u03c3\u03b7 \u03bc\u03c5\u03bf\u03c3\u03af\u03c4\u03b9\u03b4\u03b1.<\/p>\n\n\n\n

*\u039f \u03b4\u03c1 \u039a\u03bb\u03b5\u03cc\u03c0\u03b1\u03c2 \u0391. \u039a\u03bb\u03b5\u03cc\u03c0\u03b1, \u03b5\u03af\u03bd\u03b1\u03b9 \u0391\u03bd\u03ce\u03c4\u03b5\u03c1\u03bf\u03c2 \u039d\u03b5\u03c5\u03c1\u03bf\u03bb\u03cc\u03b3\u03bf\u03c2, \u0394\u03b9\u03b5\u03c5\u03b8\u03c5\u03bd\u03c4\u03ae\u03c2 \u03a4\u03bc\u03ae\u03bc\u03b1\u03c4\u03bf\u03c2 \u039d\u03b5\u03c5\u03c1\u03bf\u03b5\u03c0\u03b9\u03c3\u03c4\u03b7\u03bc\u03ce\u03bd \u03ba\u03b1\u03b9 \u03a3\u03c5\u03bd\u03c4\u03bf\u03bd\u03b9\u03c3\u03c4\u03ae\u03c2 \u03c4\u03bf\u03c5 \u039a\u03ad\u03bd\u03c4\u03c1\u03bf\u03c5 \u039d\u03b5\u03c5\u03c1\u03bf\u03bc\u03c5\u03ca\u03ba\u03ce\u03bd \u03a0\u03b1\u03b8\u03ae\u03c3\u03b5\u03c9\u03bd \u03c4\u03bf\u03c5 \u0399\u03bd\u03c3\u03c4\u03b9\u03c4\u03bf\u03cd\u03c4\u03bf\u03c5 \u039d\u03b5\u03c5\u03c1\u03bf\u03bb\u03bf\u03b3\u03af\u03b1\u03c2 \u039a\u03cd\u03c0\u03c1\u03bf\u03c5 (\u0399\u039d\u0393\u039a)<\/p>\n\n\n\n

\u03a0\u03b7\u03b3\u03ae: \u03a6ilenews<\/p>\n\n\n\n

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\"\"<\/a><\/figure>\n<\/div>\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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T\u03b1 \u03c3\u03c5\u03bc\u03c0\u03c4\u03ce\u03bc\u03b1\u03c4\u03b1 \u03b5\u03bc\u03c6\u03b1\u03bd\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c5\u03bd\u03ae\u03b8\u03c9\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03b7\u03bb\u03b9\u03ba\u03af\u03b1 […]<\/p>\n","protected":false},"author":2,"featured_media":3438,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[451],"tags":[1154,1152,1153],"class_list":["post-3437","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-451","tag-duchenne","tag-1152","tag-1153"],"yoast_head":"\nE\u03bb\u03c0\u03af\u03b4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03b1\u03bd\u03b1\u03c7\u03b1\u03af\u03c4\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 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